April is a smart aspiring journalist in her 20s who tries to balance her ambitious career with her family, which includes her widowed mom, rebellious little sister, and her grandmother. We meet April at a pivotal moment in her life: she's landed a fantastic opportunity to impress her hard-nosed Boston newspaper editor and an office romance with her super-sexy co-worker Dominic is just beginning to blossom. In an unexpected twist of fate, April lands in the hospital where her estranged uncle George works as an oncologist, and she learns the devastating news that she has cancer. The series follows April through her journey in the face of this daunting revelation, during a time in her life when the challenges of finding love and success would be enough to keep any girl occupied. But April is determined to fight and refuses to give up her dreams and goals. In the Season 2 finale, April and Beth prepare for their trip to Rome. Meanwhile, Greer returns with news that she's moving back to Boston; and Brenna feels both excited and conflicted about Finn. April’s old college pal visits her, and soon the rivalry that existed between then reignites. Elsewhere, Beth’s job and relationship are in jeopardy after she receives some disturbing news. April is reluctant to accept a literary agent's advice about her book until a meeting with a friend changes her point of view; Brenna confronts her feelings about her father. April ruffles family feathers when she investigates a secret George has been hiding; George and Mae try to work through their damaged relationship. April uses her new financial security to do anything and everything she can do feel good again.