(reUpload) Coursera - Virology I How Viruses Work
- CategoryOther
- TypeTutorials
- LanguageEnglish
- Total size3.7 GB
- Uploaded ByGigaWail
- Downloads77
- Last checkedNov. 09th '19
- Date uploadedNov. 08th '19
- Seeders 6
- Leechers13
Virology I: How Viruses Work
Columbia University via Coursera
Overview
This introductory virology course emphasizes the common reactions that must be completed by all viruses for successful reproduction within a host cell and survival and spread within a host population. The molecular basis of alternative reproductive cycles are presented with examples drawn from a set of representative animal and human viruses, although selected bacterial viruses will be discussed.
This offering has been a top-ten iTunes U Course in sciences pretty much since its release in 2012, with over 80,000 subscriptions. The course will be ported to the Coursera platform in two parts and will allow interested online students to take the course as a cohort for the first time.
Syllabus
Week 1 Welcome to virology
What is a virus?
Viruses then and now
Week 2 The infectious cycle
Assay of viral infectivity
Measurement of virions and their components
Revolutionary methods
One-step growth cycle
Week 3
The Baltimore scheme
DNA virus genomes
RNA virus genomes
Viral genetics
Week 4
Structure
The tools of structural virology
Helical symmetry
Icosahedral symmetry
Enveloped virions
Complex virions
Week 5
Attachment to cells
Entry into cells
Acid-catalyzed fusion
A new paradigm for entry
Entry of non-enveloped virions
Entering the nucleus
Week 6
Viral RNA synthesis
RNA polymerization
Plus strand RNA synthesis
Negative strand RNA synthesis
RNA synthesis of dsRNA genomes
RNA synthesis as a source of diversity
Week 7
DNA basics
Lessons from SV40
Priming via DNA or protein
Viral origins
Big DNA viruses
Regulation of DNA synthesis
Week 8
Transcription
Initiation of transcription
Viral transcription regulation
Capping and polyadenylation
Pre-mRNA splicing
Week 9
Reverse transcriptase
Retroviruses
Reverse transcription
Integration
The provirus
Hepatitis B virus
Week 10
End-dependent initiation of protein synthesis
Other decoding mechanisms
One mRNA, one protein?
Maximizing coding capacity of the viral genome
Regulation of translation: eIF2alpha
How viruses regulate cell translation
MicroRNAs
Week 11
Principles of virion assembly
Getting to the right place
Making sub-assemblies
Concerted assembly: Budding
Genome packaging
Acquisition of an envelope and egress
Code:
Unique ID : 93831677234743988621206388104317029954 (0x469752DD780983B3BE758E7301C2CE42)
Format : WebM
Format version : Version 2
File size : 10.6 MiB
Duration : 1 min 39 s
Overall bit rate mode : Variable
Overall bit rate : 890 kb/s
Writing application : Lavf52.99.1
Writing library : Lavf52.99.1
FileExtension_Invalid : webm
Video
ID : 1
Format : VP8
Codec ID : V_VP8
Duration : 1 min 39 s
Bit rate : 718 kb/s
Width : 960 pixels
Height : 540 pixels
Display aspect ratio : 16:9
Frame rate mode : Constant
Frame rate : 25.000 FPS
Compression mode : Lossy
Bits/(Pixel*Frame) : 0.055
Stream size : 8.51 MiB (81%)
Language : English
Default : Yes
Forced : No
Audio
ID : 2
Format : Vorbis
Format settings, Floor : 1
Codec ID : A_VORBIS
Duration : 1 min 39 s
Bit rate mode : Variable
Bit rate : 128 kb/s
Channel(s) : 1 channel
Sampling rate : 48.0 kHz
Compression mode : Lossy
Stream size : 1.52 MiB (14%)
Writing application : Lavc52.112.1
Writing library : libVorbis (Schaufenugget) (20101101 (Schaufenugget))
Language : English
Default : Yes
Forced : No
Code:
Code:
Files:
Virology I How Viruses Work- Virology I How Viruses Work 8.5 W8 S5 Pre-mRNA splicing (2740).mp4 (144.6 MB)
- Virology I How Viruses Work 1.1 W1 S1 Welcome to Virology (2134).mp4 (25.1 MB)
- Virology I How Viruses Work 1.2 W1 S2 What is a Virus (1439).mp4 (18.2 MB)
- Virology I How Viruses Work 1.3 W1 S3 Viruses Then and Now (1458).mp4 (18.7 MB)
- Virology I How Viruses Work 2.0 W2 Introduction.mp4 (8.0 MB)
- Virology I How Viruses Work 2.1 W2 S1 The Infectious Cycle (1707).mp4 (90.7 MB)
- Virology I How Viruses Work 2.2 W2 S2 Assay of viral infectivity (1833).mp4 (27.9 MB)
- Virology I How Viruses Work 2.3 W2 S3 Measurement of virions and their components (1420).mp4 (73.9 MB)
- Virology I How Viruses Work 2.4 W2 S4 Revolutionary methods (1423).mp4 (16.4 MB)
- Virology I How Viruses Work 2.5 W2 S5 The one-step growth cycle (1333).mp4 (70.0 MB)
- Virology I How Viruses Work 3.0 W3 Introduction.mp4 (2.3 MB)
- Virology I How Viruses Work 3.1 W3 S1 The Baltimore scheme (1722).mp4 (19.8 MB)
- Virology I How Viruses Work 3.2 W3 S2 DNA virus genomes (1439).mp4 (17.0 MB)
- Virology I How Viruses Work 3.3 W3 S3 RNA virus genomes (1310).mp4 (61.8 MB)
- Virology I How Viruses Work 3.4 W3 S4 Viral genetics (1532).mp4 (82.5 MB)
- Virology I How Viruses Work 4.0 W4 Introduction.mp4 (7.9 MB)
- Virology I How Viruses Work 4.1 W4 S1 Structure (1300).mp4 (66.9 MB)
- Virology I How Viruses Work 4.2 W4 S2 The tools of structural virology (836).mp4 (46.8 MB)
- Virology I How Viruses Work 4.3 W4 S3 Helical symmetry (1214).mp4 (64.8 MB)
- Virology I How Viruses Work 4.4 W4 S4 Icosahedral symmetry (1233).mp4 (64.3 MB)
- Virology I How Viruses Work 4.5 W4 S5 Enveloped virions (806).mp4 (43.6 MB)
- Virology I How Viruses Work 4.6 W4 S6 Complex virions (1326).mp4 (69.9 MB)
- Virology I How Viruses Work 5.0 W5 Introduction.mp4 (5.9 MB)
- Virology I How Viruses Work 5.1 W5 S1 Attachment to cells (1402).mp4 (73.2 MB)
- Virology I How Viruses Work 5.2 W5 S2 Entry into cells (1159).mp4 (62.4 MB)
- Virology I How Viruses Work 5.3 W5 S3 Acid-catalyzed fusion (1335).mp4 (72.3 MB)
- Virology I How Viruses Work 5.4 W5 S4 A new paradigm for entry (436).mp4 (21.6 MB)
- Virology I How Viruses Work 5.5 W5 S5 Entry of non-enveloped virions (1025).mp4 (54.0 MB)
- Virology I How Viruses Work 5.6 W5 S6 Entering the nucleus (327).mp4 (15.9 MB)
- Virology I How Viruses Work 6.0 W6 Introduction.mp4 (8.2 MB)
- Virology I How Viruses Work 6.1 W6 S1 Viral RNA synthesis (1204).mp4 (60.6 MB)
- Virology I How Viruses Work 6.2 W6 S2 RNA polymerization (1217).mp4 (63.1 MB)
- Virology I How Viruses Work 6.3 W6 S3 Plus strand RNA synthesis (1600).mp4 (83.2 MB)
- Virology I How Viruses Work 6.4 W6 S4 Negative strand RNA synthesis (1357).mp4 (69.2 MB)
- Virology I How Viruses Work 6.5 W6 S5 RNA synthesis from dsRNA genomes (433).mp4 (23.9 MB)
- Virology I How Viruses Work 6.6 W6 S6 RNA synthesis as a source of diversity (704).mp4 (30.3 MB)
- Virology I How Viruses Work 7.0 W7 Introduction.mp4 (8.3 MB)
- Virology I How Viruses Work 7.1 W7 S1 DNA basics (2357).mp4 (124.3 MB)
- Virology I How Viruses Work 7.2 W7 S2 Lessons from SV40 (2118).mp4 (111.7 MB)
- Virology I How Viruses Work 7.3 W7 S3 Priming via DNA or protein (1851).mp4 (98.9 MB)
- Virology I How Viruses Work 7.4 W7 S4 Viral origins (1448).mp4 (77.9 MB)
- Virology I How Viruses Work 7.5 W7 S5 Big DNA viruses (1727).mp4 (91.6 MB)
- Virology I How Viruses Work 7.6 W7 S6 Regulation of DNA synthesis (2432).mp4 (128.6 MB)
- Virology I How Viruses Work 8.0 W8 Introduction.mp4 (11.2 MB)
- Virology I How Viruses Work 8.1 W8 S1 Transcription (843).mp4 (45.8 MB)
- Virology I How Viruses Work 8.2 W8 S2 Initiation of transcription (1627).mp4 (85.8 MB)
- Virology I How Viruses Work 8.3 W8 S3 Viral transcription regulation (2245).mp4 (118.7 MB)
- Virology I How Viruses Work 8.4 W8 S4 Capping and polyadenylation (1002).mp4 (8.8 MB)
- Virology I How Viruses Work 1.0 W1 Introduction.mp4 (10.6 MB)
- Virology I How Viruses Work 9.0 W9 Introduction.mp4 (8.6 MB)
- Virology I How Viruses Work 9.1 W9 S1 Reverse transcriptase (1101).mp4 (56.7 MB)
- Virology I How Viruses Work 9.2 W9 S2 Retroviruses (1518).mp4 (80.1 MB)
- Virology I How Viruses Work 9.3 W9 S3 Reverse transcription (1439).mp4 (67.0 MB)
- Virology I How Viruses Work 9.4 W9 S4 Integration (1141).mp4 (58.4 MB)
- Virology I How Viruses Work 9.5 W9 S5 The provirus (946).mp4 (51.9 MB)
- Virology I How Viruses Work 9.6 W9 S6 Hepatitis B virus (948).mp4 (51.9 MB)
- Virology I How Viruses Work 10.0 W10 Introduction.mp4 (7.1 MB)
- Virology I How Viruses Work 10.1 W10 S1 End-dependent initiation of protein synthesis (1339).mp4 (70.6 MB)
- Virology I How Viruses Work 10.2 W10 S2 Other decoding mechanisms (1723).mp4 (91.3 MB)
- Virology I How Viruses Work 10.3 W10 S3 One mRNA one protein (734).mp4 (39.6 MB)
- Virology I How Viruses Work 10.4 W10 S4 Maximizing coding capacity of the viral genome (1654).mp4 (89.0 MB)
- Virology I How Viruses Work 10.5 W10 S5 Regulation of translation eIF2alpha (1141).mp4 (61.5 MB)
- Virology I How Viruses Work 10.6 W10 S6 How viruses regulate cell translation (641).mp4 (36.1 MB)
- Virology I How Viruses Work 10.7 W10 S7 MicroRNAs (645).mp4 (35.8 MB)
- Virology I How Viruses Work 11.0 W11 Introduction.mp4 (14.1 MB)
- Virology I How Viruses Work 11.1 W11 S1 Principles of virion assembly (1147).mp4 (61.6 MB)
- Virology I How Viruses Work 11.2 W11 S2 Getting to the right place (643).mp4 (35.2 MB)
- Virology I How Viruses Work 11.3 W11 S3 Making sub-assemblies (1501).mp4 (77.9 MB)
- Virology I How Viruses Work 11.4 W11 S4 Concerted assembly budding (1147).mp4 (60.9 MB)
- Virology I How Viruses Work 11.5 W11 S5 Genome packaging (1542).mp4 (81.7 MB)
- Virology I How Viruses Work 11.6 W11 S6 Acquisition of an envelope and egress (1321).mp4 (67.5 MB)
- virology-Ashlee_Study_Stuff-BYOE enzymes .pdf (398.7 KB)
- virology-Ashlee_Study_Stuff-Guide to Reverse Transcriptions.pdf (261.3 KB)
Code:
- udp://tracker.leechers-paradise.org:6969/announce